Crystal Palace will be hoping to avoid a ninth straight defeat at the hands of Chelsea when the two neighbours clash in a London derby at Selhurst Park on Saturday, February 19.

Manchester United will be looking to extend their long unbeaten run against Southampton when they clash at Old Trafford on Saturday, February 12.
 

Crystal Palace will be hoping that Liverpool experience an off day when they meet in the Premier League at Selhurst Park on January 23.
 

Burnley will be seeking only their second Premier League win of the season when they host out-of-sorts Leicester at Turf Moor on January 15.

West Ham United will be eager to build on what they achieved in 2021 with a positive result against Crystal Palace in a London derby at Selhurst Park on Saturday, 01 January 2022. 

Chelsea FC will square off with Brighton and Hove Albion in an English Premier League match on December 29.

 

Tottenham Hotspur will be looking to maintain their unbeaten start under Antonio Conte when Crystal Palace make the short trip across London to the Tottenham Hotspur Stadium on December 26.

Manchester United will be aiming to build on their new found confidence under interim coach Ralf Rangnick when they host Brighton & Hove Albion in a 2021/22 English Premier League match at Old Trafford on Saturday afternoon. 

West Ham United will feel that Arsenal are there for the taking when they clash in a London derby at the Emirates Stadium on December 15.

The battle to become the kings of English football in the 2021/22 season has seen three teams emerge as the strong contenders for the Premier League title.